https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Advances in oral drug delivery for regional targeting in the gastrointestinal tract - influence of physiological, pathophysiological and pharmaceutical factors https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38577 Wed 22 Mar 2023 17:23:53 AEDT ]]> Influence of cigarette smoking on the human duodenal mucosa-associated microbiota https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33993 Firmicutes, specifically Streptococcus and Veillonella spp. The relative abundance of the genus Rothia was also observed to be greater in current smokers; while in contrast, levels of Prevotella and Neisseria were lower. The MAM profiles and diversity of previous smokers were observed to be intermediate between current and never smokers. Smoking did not impact the total density of bacteria present on the mucosa. Conclusions: These data indicate the duodenal MAM of current smokers is characterised by reduced bacterial diversity, which is partially but not completely restored in previous smokers. While the precise mechanisms remain to be elucidated, these microbiota changes may in some part explain the adverse effects of smoking on mucosa-associated diseases of the GI tract. Smoking status requires consideration when interpreting MAM data.]]> Tue 03 Sep 2019 17:58:12 AEST ]]> Dyspepsia and the microbiome: time to focus on the small intestine (letter) https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:24504 Sat 24 Mar 2018 07:13:11 AEDT ]]> Small Intestinal Bacterial Overgrowth in Functional Dyspepsia: A Systematic Review and Meta-Analysis https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:49370 Fri 12 May 2023 13:38:14 AEST ]]>